Another Side Of Lipofuscin Age Pigments
Lipofuscin, the age pigments (plural) that clog up lysosomes, mitochondria, and the cytoplasm of cells, can’t form without polyunsaturated fatty acids, especially highly-unsaturated fatty acids (docosahexaenoic acid, docosapentaenoic acid, eicosapentaenoic acid, and alpha-linolenic acid).
But every dark cloud has a silver lining, and the same goes for lipofuscin.
S.M. Guarino, F.M. Guarino, G. Tommonaro, & M. de Nicola (“Cadmium-induced lipofuscins and effect of zinc on hepatopancreas cells in Idotea baltica,” Experientia, Sept. 1995) wrote …
“Lipofuscin has an important role in the compartmentalization of heavy metals.”
According to the same source …
“A comparison of lipofuscin induction by cadmium and by copper showed that cadmium has a weaker peroxidative action than copper. The effect of cadmium was reduced by the simultaneous presence of zinc, which on its own was ineffective in lipofuscin induction.”
Almost every mineral accelerates aging, to a greater or lesser degree, something I’ve been beating the drum about since starting Atom’s Blog in 2011.
Cancer is the accelerator, and aging is the brakes, and driving a car without the latter is a dangerous proposition.
J.B. Brennick, J.X. O’Connell, G.R. Dickersin, B.Z. Pilch, R.H. Young (“Lipofuscin pigmentation (so-called ‘melanosis’) of the prostate,” The American Journal of Surgical Pathology, May 1994) wrote …
“Although intraepithelial pigment in prostatic biopsy or resection specimens is usually considered characteristic of seminal vesicle epithelium, our study demonstrates that lipofuscin is commonly present in epithelial cells of benign prostatic hyperplasia and less frequently in those of prostatic intraepithelial neoplasia and adenocarcinoma.”
There’s a better time of the day to be young and acidic, and a better time of the day to be old and alkaline.
Just remember to walk big circles around Yellow Fat Disease.