Half Life Of Lipofuscin
By Atom Bergstrom
Re: My age spots are increasing. I was hoping that, given the four-year half life of PUFAs, I would have excreted much of it out of my body in the last ten years of being careful.
Tissues and organs do not all age at a uniform rate.
Organs can be decades apart in aging, depending on the weakest link in macromolecules.
Omega 3 fatty acids are mildly toxic, but other factors can increase their toxicity exponentially.
So my first questions are …
“How much sun exposure have you had?”
“Are you living in a windy or dry climate that can dehydrate the skin?”
“How much iron and manganese are in your diet?”
“Do you have ‘Heart Lines’ in your earlobes?”
“Do you have any ‘A-framed’ toenails?”
The dermis and the hypodermis are especially vulnerable to stress hormones because they are part of the adrenal medulla — “part of,” not “connected to,” the adrenal medulla.
Think of omega 3 fatty acids as the building blocks, and a variety of chemicals as the construction machinery …
estrogen, serotonin, melatonin, nitric oxide, histamine, cortisol, adrenaline, noradrenaline, acetylcholine, catecholamines, advanced glycation end-products (AGEs), etc.
The half life of omega 3 fatty acids is not the same as the half life of lipofuscin.
Apoptosis and autophagy are the preferred way of eliminating lipofuscin.
Necrosis, oncosis, and pyroptosis eliminate lipofuscin but generate its production in surrounding cells via inflammation — not a good idea!