Fat-Holding Pigment #2

By Atom Bergstrom

Atom’s Blog

Despite the divergence of opinion over a hundred years ago, scientists knew more about Yellow Fat Disease than they know today.

And an even greater divergence of opinion exists today.

But one thing IS for sure — Yellow Fat Disease measures the velocity of aging.


Subhash Kashyap, Vinay Shanker, & Neeraj Sharma (“Hutchinson-Gilford progeria syndrome,” Indian Dermatology Online Journal, Oct.-Dec. 2014) wrote …

“Hutchinson-Gilford Progeria Syndrome is a rare genetic disorder characterized by premature aging involving the skin, bones, heart, and blood vessels. We report a three-year-old boy with clinical manifestations characteristic of this syndrome. He had a characteristic ‘plucked-bird’ appearance, prominent eyes and scalp veins, senile look, loss of scalp hair, eyebrows, and eyelashes, stunted growth, and mottled pigmentation with sclerodermatous changes over the trunk and lower limbs.”

According to the same source …

“Radiography changes manifest within the second year of life. There is diffuse osteopenia, acro-osteolysis of the phalanges and distal clavicles, but bone age is normal. Hyaluronic acid excretion is increased from fibroblasts and there is extensive lipofuscin deposition.”


David H. Dolley & Frances V. Guthrie (“The Pigmentation of Nerve Cells,” The Journal of Medical Research, Sept. 1918) wrote …

“For Sehrt the pigment of nerve cells is seemingly entirely a fat-holding pigment, though his notes on the substantia nigra, for example, read as follows: ‘In many cases there is no reaction. In others great diversity of colorability. Often only the finest granular pigment of the smallest cells is colored, while the larger pigment masses remain completely negative; yet here there is in some cases a most intense reaction.’ With age, he says, the pigment becomes somewhat similar to the melanotic, but the inference appears to be that there is no melanin proper. In short, he generalizes from a part to the whole, a criticism which is also made by Hueck (p. 72).

“Oberndorfer (’02), working rather incidentally with the local ganglion cells in a study of the seminal vesicles, rested his conclusion of the combination of their pigment with fat solely upon the osmic-acid reaction.

“Obersteiner (’03, ’04) distinguished the same forms of pigment as Rosin, a dark brown and a light yellow. According to him, the dark-brown pigment occurs in two places, the substantia nigra and the locus caeruleus, the yellow fatty pigment in the remaining parts of the nervous system.

“Calligaris (’08) made also the distinction between the yellow ‘pseudo-pigment, lipochrome,’ and the black ‘true’ pigment (as cited by Hueck), the latter a melanin. He describes the black pigment as present in the vagus nucleus, the spinal ganglia, the locus caeruleus and the substantia nigra, while the fatty pigment may occur with it.

“Neumann (’09) found a lipochrome, reacting blue with iodin[e], but otherwise characteristically, to be a widespread and regular constituent of spinal and sympathetic ganglion cells of the frog. It was identical with the pigment both of atrophic fatty tissue and of the cells of Schwann’s sheath of the nerve fiber, but different from the fatty pigment in mammals. He also accepts the occurrence of non-fatty pigment in mammals.

“The position of Mühlmann (’11) is quite opposed to the predominant conclusion of the duality of pigment. He maintains that the pigments are identical, that it is all a fatty pigment at the beginning, but that with age the fatty property is lost. The tacit inference, Hueck says, is that the melanotic gradually develops out of the fatty.

“The work of Hueck (’12) is an extensive microchemical study of the various endogenous pigments. The collective survey enables him to point out clearly the confusion and error resulting from limited and one-sided investigations, and his paper abounds in points relevant to our own study, which must be passed over. Hueck determines a melanin and a lipofuscin in nerve cells. The melanin has no characteristic which distinguishes it from melanin elsewhere, and must be placed in that group until new reactions become known. Further, the melanin is not limited in distribution to any particular regions, in opposition to the common belief which has cropped out in the preceding reports, but which our work wholly discredits. There are, however, the same variations of distribution which will receive later attention.

“The term lipofuscin is Borst’s. It refers to the brown waste pigments which through oxidation are converted from lipoid substances or perhaps fatty acids. Hueck regards the lipofuscin as a normal finding, — a ‘wear-and-tear’ product in the physiological sense. It is not always easy to distinguish between the melanin and the lipofuscin, and they may be very intimately mixed — even the same granule may contain both. The processes of formation also tend to occur together, though each pigment was found separately. This work was also done on human material.”

(To Be Continued)


'Fat-Holding Pigment #2' have 5 comments

  1. May 8, 2020 @ 4:09 am Atom

    Health requires two things.
    “One, a hostility discharge, just like in Gestalt therapy, Alexander Lowen, etc., etc.
    “Two, it requires forgiveness — biological forgiveness, not psychological forgiveness — to deal with any residual guilt.


  2. May 8, 2020 @ 4:10 am Atom

    Re: Nothing would cause over-alkalinity That’s a false statement that we can be too alkaline. Nonsense. 100%.
    Vomiting causes death by alkalosis.
    Altitude sickness causes alkalosis.
    Salicylate poisoning causes alkalosis.
    Diuretic overuse causes alkalosis.
    Excessive sweating causes alkalosis. Hundreds of marathon runners have died from it.
    Diarrhea causes alkalosis. There are exceptions to the rule: Diarrhea from cholera causes acidosis.
    Potassium loss causes hypokalemic alkalosis.
    Alcohol abuse causes alkalosis.
    Milk-alkali syndrome causes alkalosis. Untreated milk-alkali syndrome leads to kidney failure or death.
    Millions of people died of metabolic alkalosis due to the milk + alkaline diet concocted by gastroenterologist Bertram Welton Sippy (1866–1924) to “treat” gastric and duodenal ulcers. The diet was followed for decades. Dr. Sippy made an honest mistake, since the Assassins In White can’t make big bucks out of moo glue and bland food.
    Calcium supplementation has caused a dramatic return of metabolic alkalosis from milk-alkali syndrome. (It’s still called milk-alkali syndrome although no milk need be involved.)
    Magnesium supplementation has also caused a return of metabolic alkalosis from milk-alkali syndrome.
    “A high level of vitamin D in the body, such as from taking supplements, can worsen milk-alkali syndrome,” according to MedlinePlus.
    “By 1985 with the widespread use of proton-pump inhibitors and antibiotic therapies for peptic ulcer disease, the milk-alkali syndrome essentially disappeared, accounting for less than 1% of hypercalcemia cases. However, now, the syndrome has again risen in clinical importance as the third most common cause of hypercalcemia behind malignancy [CANCER] and primary hyperparathyroidism,” according to an article in The Journal of General Internal Medicine (May 5, 2007). Wait a minute! Malignancy? Cancer? I thought cancer couldn’t exist in an alkaline body? I read it on the internet. It MUST be true!
    Alkaloid abuse results in metabolic alkalosis. According to the Clinical Kidney Journal (“Heroin crystal nephropathy, Jun. 2015), “Urine microscopy showed numerous broomstick-like crystals. These crystals are also identified in light and electron microscopy. We hypothesize that heroin crystalizes in an alkaline pH, resulting in tubular obstruction and acute kidney injury. Management is mainly supportive as there is no known specific therapy for this condition.”
    That’s just for starters.


  3. May 8, 2020 @ 4:11 am Atom

    Here are comments gleaned from cyberspace …
    “It’s amazing how bad reflux can be on our other systems.”
    “My stomach ballooned out and my ears popped.”
    “GERD will cause a feeling of pressure in the ears if you fill your stomach too much.”
    “Have you had these pressure problems or the heartbeat-in-the-ear problem with your GERD?”
    “Heartburn due to stomach problems may cause hoarseness, swallowing difficulties, throat pain, and sinus infections.”
    “Ear pain and heartburn sometimes go hand in hand.”
    “Upper back pain is not uncommon when suffering from acid reflux/heartburn.”
    “When my throat pain gets bad the back pain comes on.”
    “Chest pain is a classic acid reflux symptom.”
    Our internal organs need to inhale and exhale too.
    They suffer if excess gas pressure restricts them from dilating and constricting.
    Why is heartburn more common among the elderly and pregnant?
    Perhaps if the elderly would stretch and yawn more often they wouldn’t be so elderly anymore.
    Yawning and stretching won’t make a pregnant woman less pregnant, but it will relieve her heartburn.
    “Elderly” is often a code word for central obesity, overcrowding the abdomen and squeezing the stomach and other organs, including the heart..
    An enlarged uterus overcrowds the abdomen and does the same.
    A truck tire filled with air can feel just as “hard” as one made of solid rubber.


  4. May 8, 2020 @ 4:14 am Atom

    A neurologist came to see me with three problems.

    He explained, “I have a migraine headache. There’s a painful bump behind my knee, and my knuckles are swollen.”

    He grasped the ring finger of his RIGHT hand while complaining about his “knuckles” (plural).

    The body’s anterior right side and posterior left side register psychosomatic traumas with women, so it was obvious that he had an emotional “charge” from an unresolved issue with a woman.

    The ring finger is the Triple Heater Meridian’s primary “commitment” reflex, which is why a wedding ring signifies, “I only have heat for you” or “I’m only in heat for you.”

    “Which specific knuckle is swollen?” I asked.

    “All of them,” he replied, still holding only his ring finger.

    “Which knuckle did the problem start on?” I indirectly persisted.

    He noticed that he was grasping his ring finger, and said, “Well, it started on this one.”

    “Did you recently get a divorce?” I pried.

    “Yes, I did,” he replied,

    I held his right knee while he sat in a chair, and extended his leg outward and inward a dozen or more times, fast and forcefully on the way out, and exaggeratedly slow on the return.

    The bump behind his knee disappeared, but I said nothing.

    Next came muscle response testing, and the sole weak muscle was his pectoralis major clavicular, associated with the Stomach Meridian.

    “That’s interesting, because I recently had gastritis,” he commented.

    “Before or after your wife left you?” I asked.

    “After,” he replied.

    “Do you miss her cooking?” I continued.

    “Well, yes, I do. She was a really good cook.” he reminisced.

    (I had a friend who had most of his stomach surgically removed because he couldn’t deal with a girlfriend who refused to cook for him.)

    He returned to his chair (I had muscle-tested him on the floor) and reached for the back of his knee while asking, “Now what about this?”

    But to his astonishment, the bump had completely disappeared.

    “Where did it go?” he exclaimed.

    “You know,” I laughed. “You were ready to let this go before you even came to see me.

    “You were like an apple on a tree you only have to touch and it falls into your hand.

    “That’s why your knee problem resolved so quickly.

    “All you wanted to do was kick your ex-wife one final boot out the door!

    “Goodbye. Adios. So long.

    “Time to move on to something new.

    “All it took was mimicking a swift kick by moving your knee back and forth, which is what I did.

    “If you hadn’t been so ready to let her go, you might have had to kick something a hundred or even a hundred thousand times — however long it takes to discharge the repressed anger.

    “And, if you were still living with her, it could be an ongoing stockpiling of hostility unless you both resolved your issues.

    “Health requires two things.

    “One, a hostility discharge, just like in Gestalt therapy, Alexander Lowen, etc., etc.

    “Two, it requires forgiveness — biological forgiveness, not psychological forgiveness — to deal with any residual guilt.

    “Once a hostility is discharged, the guilt problem must still be resolved.

    “And after forgiveness, the hostility often returns.

    “Discharge it repeatedly, however long it takes, but always follow a hostility discharge with forgiveness to end any guilt feedback.”


  5. May 8, 2020 @ 4:16 am Atom

    Re: How can you tell if your Muscle Response Tester is competent? Be practical. Give him the “Dirty Thirty Test.” Fill ten opaque capsules with vitamin C powder. Fill ten opaque capsules with syrup of ipecac emetic. Fill ten opaque capsules with Ex-Lax Maximum Strength sennosides. Have him Muscle Response Test which ten are OK for you, then ask your Muscle Response Tester to swallow the ten capsules he selected.


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